| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0591 | PP_3662 | PP_0591 | PP_3662 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Homologs of previously reported genes of unknown function; Unknown function. | 0.900 |
| PP_0591 | apt | PP_0591 | PP_4266 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.947 |
| PP_0591 | ppnP | PP_0591 | PP_4248 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.910 |
| PP_0591 | ushA | PP_0591 | PP_1414 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 5'-nucleotidase - 2',3'-cyclic phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines, pyrimidines, nucleosides, and nucleotides; Belongs to the 5'-nucleotidase family. | 0.712 |
| PP_0591 | xdhB | PP_0591 | PP_4279 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.933 |
| PP_0591 | xpt | PP_0591 | PP_5265 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.737 |
| PP_0591 | yrfG | PP_0591 | PP_0259 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Purine nucleotidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.534 |
| PP_3662 | PP_0591 | PP_3662 | PP_0591 | Homologs of previously reported genes of unknown function; Unknown function. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.900 |
| PP_3662 | apt | PP_3662 | PP_4266 | Homologs of previously reported genes of unknown function; Unknown function. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.904 |
| PP_3662 | ppnP | PP_3662 | PP_4248 | Homologs of previously reported genes of unknown function; Unknown function. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.913 |
| PP_3662 | pydA | PP_3662 | PP_4038 | Homologs of previously reported genes of unknown function; Unknown function. | NADP-dependent dihydropyrimidine dehydrogenase subunit PreA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.903 |
| PP_3662 | pyrR | PP_3662 | PP_4997 | Homologs of previously reported genes of unknown function; Unknown function. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Function of strongly homologous gene; regulator. | 0.900 |
| PP_3662 | upp | PP_3662 | PP_0746 | Homologs of previously reported genes of unknown function; Unknown function. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.901 |
| PP_3662 | ushA | PP_3662 | PP_1414 | Homologs of previously reported genes of unknown function; Unknown function. | 5'-nucleotidase - 2',3'-cyclic phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines, pyrimidines, nucleosides, and nucleotides; Belongs to the 5'-nucleotidase family. | 0.900 |
| apt | PP_0591 | PP_4266 | PP_0591 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.947 |
| apt | PP_3662 | PP_4266 | PP_3662 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Homologs of previously reported genes of unknown function; Unknown function. | 0.904 |
| apt | ppnP | PP_4266 | PP_4248 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.907 |
| apt | upp | PP_4266 | PP_0746 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.626 |
| apt | ushA | PP_4266 | PP_1414 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase - 2',3'-cyclic phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines, pyrimidines, nucleosides, and nucleotides; Belongs to the 5'-nucleotidase family. | 0.913 |
| apt | xpt | PP_4266 | PP_5265 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.529 |