STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4249Homologs of previously reported genes of unknown function. (230 aa)    
Predicted Functional Partners:
ccoN-I
Cytochrome c oxidase subunit I, cbb3-type; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the heme-copper respiratory oxidase family.
  
    0.621
ccoP-I
Cytochrome c oxidase subunit, cbb3-type; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
  
    0.599
ccoO-I
Cytochrome c oxidase subunit, cbb3-type; Function of strongly homologous gene; enzyme.
  
    0.571
ccoQ-I
Cytochrome c oxidase subunit, cbb3-type; Function of strongly homologous gene; enzyme.
       0.568
thiD
Phosphomethylpyrimidine kinase.
  
    0.557
ccoS
Cytochrome oxidase maturation protein, cbb3-type.
 
     0.442
ccoP-II
Cytochrome c oxidase subunit, cbb3-type; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
       0.424
PP_1747
Conserved protein of unknown function, UPF0270 family; Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0270 family.
 
     0.423
alg8
Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid.
  
     0.411
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
     0.411
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.