STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aqpZAquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (230 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.803
opuA
Glycine betaine ABC transporter, ATPase/permease fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Amino acids, peptides and amines.
      
 0.750
glpD
Glycerol-3-phosphate dehydrogenase (aerobic); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.644
PP_4931
Homologs of previously reported genes of unknown function.
  
  
 0.603
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.581
ugpQ
Glycerophosphoryl diester phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.554
PP_2091
Putative Serine/threonine-protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
 
 0.547
PP_5256
Cyclic nucleotide-binding protein.
  
 0.539
fruB
Phosphotransferase system, fructose-specific EI/HPr/EIIA components; Function experimentally demonstrated in the studied genus; transporter; Energymetabolism : Sugars; Belongs to the PEP-utilizing enzyme family.
     
 0.522
PP_4283
Transcriptional regulator, GntR family.
  
    0.482
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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