| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_4283 | PP_4284 | PP_4283 | PP_4284 | Transcriptional regulator, GntR family. | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.424 |
| PP_4284 | PP_4283 | PP_4284 | PP_4283 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Transcriptional regulator, GntR family. | 0.424 |
| PP_4284 | apt | PP_4284 | PP_4266 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.458 |
| PP_4284 | purC | PP_4284 | PP_1240 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.407 |
| PP_4284 | purD | PP_4284 | PP_4823 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoribosylamine--glycine ligase. | 0.445 |
| PP_4284 | purE | PP_4284 | PP_5336 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.451 |
| PP_4284 | purK | PP_4284 | PP_5335 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.444 |
| PP_4284 | purL | PP_4284 | PP_1037 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.808 |
| PP_4284 | purM | PP_4284 | PP_1665 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.426 |
| PP_4284 | purN | PP_4284 | PP_1664 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.412 |
| PP_4284 | uraA | PP_4284 | PP_0745 | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative uracil permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.524 |
| apt | PP_4284 | PP_4266 | PP_4284 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.458 |
| apt | purC | PP_4266 | PP_1240 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.467 |
| apt | purD | PP_4266 | PP_4823 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylamine--glycine ligase. | 0.463 |
| apt | purE | PP_4266 | PP_5336 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.488 |
| apt | purK | PP_4266 | PP_5335 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.479 |
| apt | purL | PP_4266 | PP_1037 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.771 |
| apt | purM | PP_4266 | PP_1665 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.462 |
| apt | purN | PP_4266 | PP_1664 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.463 |
| purC | PP_4284 | PP_1240 | PP_4284 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Putative Transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.407 |