PP_4289 protein (Pseudomonas putida KT2440) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PP_4289

Homologs of previously reported genes of unknown function. (446 aa)

Predicted Functional Partners:

allA

0.965

pucM

0.960

pucL

0.930

puuE

0.919

xdhC

0.834

xdhB

0.823

xdhA

0.820

guaD

0.790

cysZ

0.744

cumA

0.653

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_4289	allA	PP_4289	PP_4288	Homologs of previously reported genes of unknown function.	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	0.965
PP_4289	cumA	PP_4289	PP_1034	Homologs of previously reported genes of unknown function.	Multicopper oxidase; Function experimentally demonstrated in the studied species; enzyme.	0.653
PP_4289	cysZ	PP_4289	PP_0785	Homologs of previously reported genes of unknown function.	Putative cysZ protein, required for sulfate transport; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.	0.744
PP_4289	guaD	PP_4289	PP_4281	Homologs of previously reported genes of unknown function.	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	0.790
PP_4289	pucL	PP_4289	PP_4287	Homologs of previously reported genes of unknown function.	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.930
PP_4289	pucM	PP_4289	PP_4285	Homologs of previously reported genes of unknown function.	5-hydroxyisourate hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.	0.960
PP_4289	puuE	PP_4289	PP_4286	Homologs of previously reported genes of unknown function.	Allantoinase; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.919
PP_4289	xdhA	PP_4289	PP_4278	Homologs of previously reported genes of unknown function.	Xanthine dehydrogenase subunit XdhA; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.820
PP_4289	xdhB	PP_4289	PP_4279	Homologs of previously reported genes of unknown function.	Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.823
PP_4289	xdhC	PP_4289	PP_4280	Homologs of previously reported genes of unknown function.	Xanthine dehydrogenase accessory factor; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.834
allA	PP_4289	PP_4288	PP_4289	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	Homologs of previously reported genes of unknown function.	0.965
allA	guaD	PP_4288	PP_4281	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	0.447
allA	pucL	PP_4288	PP_4287	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.938
allA	pucM	PP_4288	PP_4285	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	5-hydroxyisourate hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.	0.754
allA	puuE	PP_4288	PP_4286	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	Allantoinase; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.897
allA	xdhB	PP_4288	PP_4279	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	Xanthine dehydrogenase subunit XdhB; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.402
allA	xdhC	PP_4288	PP_4280	Ureidoglycolate lyase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.	Xanthine dehydrogenase accessory factor; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.	0.591
cumA	PP_4289	PP_1034	PP_4289	Multicopper oxidase; Function experimentally demonstrated in the studied species; enzyme.	Homologs of previously reported genes of unknown function.	0.653
cysZ	PP_4289	PP_0785	PP_4289	Putative cysZ protein, required for sulfate transport; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.	Homologs of previously reported genes of unknown function.	0.744
guaD	PP_4289	PP_4281	PP_4289	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	Homologs of previously reported genes of unknown function.	0.790