Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glxRTartronate semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. (297 aa)    
Predicted Functional Partners:
gcl
Glyoxylate carboligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the TPP enzyme family.
 
 
 0.999
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism; Belongs to the hyi family.
 
 0.999
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.996
garK
Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family.
  
 
 0.945
hprA
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.904
ghrB
2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.904
PP_3646
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 0.873
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.791
PP_2589
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 0.785
PP_2694
Aldehyde dehydrogenase family protein.
  
  
 0.770
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.