STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttuDPutative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (424 aa)    
Predicted Functional Partners:
glxR
Tartronate semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
 
 
 0.996
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.985
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism; Belongs to the hyi family.
 
  
 0.973
garK
Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family.
     
 0.944
ghrB
2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.942
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 0.932
gcl
Glyoxylate carboligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the TPP enzyme family.
 
   
 0.932
hprA
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.923
pykA
Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.
  
 
 0.909
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.902
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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