STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykPyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.994
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
  
 
 0.976
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.973
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.967
pycB
Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
 
 0.950
maeB
Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.943
ldhA
D-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.938
gmk
Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.933
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.931
tpiA
Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.931
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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