Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_4302Urea transporter. (291 aa)    
Predicted Functional Partners:
ureC
Urease subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
     
 0.841
PP_2569
Metabolite MFS transporter, MHS family.
      
 0.820
ureE
Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
     
 0.761
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.706
PP_2654
Putative Glutathione S-transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.671
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.615
glxR
Tartronate semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
       0.612
PP_4624
Putative hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
     0.610
amtB
Ammonium transporter AmtB; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds.
     
 0.550
PP_1160
Asparaginase family protein.
      
 0.548
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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