STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheZProtein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (262 aa)    
Predicted Functional Partners:
cheA
Chemotaxis histidine kinase CheA.
 
 
 0.999
cheY
Response regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair.
 
 
 0.996
PP_1492
Sensor histidine kinase/response regulator.
  
 
 0.980
PP_4988
Signal transduction histidine kinase CheA/CheY-like receiver; Function of strongly homologous gene; enzyme; Signaltransduction : Two-component systems.
  
 
 0.980
fliM
Flagellar synthesis, switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.971
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor.
 
 
 0.966
PP_4393
Putative chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.
 
 
 0.960
PP_4333
CheW domain protein.
 
  
 0.958
fliA
RNA polymerase sigma 28 (sigma F) factor for class III flagellar operons; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.957
PP_4332
Chemotaxis protein CheW.
 
  
 0.956
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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