Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
cheYResponse regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair. (124 aa)    
Predicted Functional Partners:
cheA
Chemotaxis histidine kinase CheA.
 
 0.999
cheZ
Protein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
 
 0.999
fliN
C-ring protein of the flagellar basal body; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
 0.954
mcpQ
Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpQ recognizes specifically citrate and citrate/metal(2+) complexes. Binds citrate/metal(2+) complexes with higher affinity than free citrate, and mediates preferentially chemotaxis toward citrate/metal(2+) complexes.
  
 0.938
PP_4332
Chemotaxis protein CheW.
 
 
 0.933
PP_4333
CheW domain protein.
 
 
 0.924
cheBA
Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
 
 0.912
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor.
   
 0.908
mcpU
Methyl-accepting chemotaxis transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpU is a chemoreceptor that specifically recognizes polyamines such as putrescine, spermidine and cadaverine.
  
 0.903
mcpS
Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpS is a specific chemoreceptor for 6 tricarboxylic acid (TCA) cycle intermediates (succinate, fumarate, malate, oxaloacetate, citrate and isocitrate), butyrate and acetate. Malate, succinate, fumarate and oxaloacetate cause the strongest chemotactic response.
  
 0.887
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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