STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheYResponse regulator for chemotactic signal transduction; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein modification and repair. (124 aa)    
Predicted Functional Partners:
cheA
Chemotaxis histidine kinase CheA.
 
 0.998
cheZ
Protein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
 
 
 0.996
fliN
C-ring protein of the flagellar basal body; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
 0.944
PP_4332
Chemotaxis protein CheW.
 
 
 0.920
cheBA
Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
 
 0.900
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor.
   
 0.895
PP_4333
CheW domain protein.
 
 
 0.880
PP_1651
Two-component response regulator; Function of strongly homologous gene; regulator; Regulatory functions.
  
   
 0.870
PP_2257
Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 0.870
PP_4521
Putative aerotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 0.852
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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