Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_4363Sensor histidine kinase/response regulator. (563 aa)    
Predicted Functional Partners:
PP_4364
Putative Anti-sigma F factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.999
PP_4362
Homologs of previously reported genes of unknown function.
 
 0.995
gacS
Sensor protein GacS.
 
 
0.956
PP_3413
Sensor histidine kinase/response regulator.
  
 
 0.954
PP_3728
Sensor histidine kinase/response regulator.
  
 
 0.950
fliG
Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.888
fliM
Flagellar synthesis, switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.886
fleS
Sensory box histidine kinase FleS.
 
 
 0.878
fliH
Flagellar assembly protein FliH.
 
  
 0.870
flgJ
Peptidoglycan hydrolase FlgJ.
  
  
 0.867
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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