STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flgMNegative regulator of flagellin synthesis FlgM. (104 aa)    
Predicted Functional Partners:
fliA
RNA polymerase sigma 28 (sigma F) factor for class III flagellar operons; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
 0.999
PP_4396
Homologs of previously reported genes of unknown function.
  
  
 0.988
fliS
Flagellar chaperone, inhibits premature FliC assembly; Function experimentally demonstrated in the studied genus; factor; Cellenvelope : Surface structures.
 
 
 0.981
flgA
Flagella basal body P-ring formation protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
 
  
 0.979
fliC
Flagellin, filament structural protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
  
 0.955
fliD
Flagellar filament capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.947
PP_5209
Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.941
fliL
Flagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.939
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.933
ycgR
Flagellar brake protein YcgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity). Binds c-di-GMP with a dissociation constant of 165 nM. Binds 2 intercalated (c-di-GMP) dimers per subunit.
 
  
 0.932
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.