STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpdVDihydrolipoyl dehydrogenase component of branched-chain alpha-keto acid dehydrogenase complex; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (459 aa)    
Predicted Functional Partners:
aceF
AceF-S-acetyldihydrolipoate; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
bkdAB
Branched-chain alpha-keto acid dehydrogenase complex, beta subunit; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 0.998
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 0.998
bkdAA
Branched-chain alpha-keto acid dehydrogenase complex, alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
 0.996
sucB
2-oxoglutarate dehydrogenase dihydrolipoyltranssuccinylase subunit; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.995
sucA
2-oxoglutarate decarboxylase, thiamine-requiring E1 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : TCA cycle.
 
 0.983
acoC
Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system.
 
 0.979
gcvH-II
Glycine cleavage system H protein 2; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.975
gcvH-I
Glycine cleavage system H protein 1; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.973
gcvP-II
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity); Belongs to the GcvP family.
  
 
 0.949
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.