STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_4462Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (221 aa)    
Predicted Functional Partners:
PP_4463
Carbon-nitrogen hydrolase family protein.
  
    0.784
gllB
4-oxalmesaconate hydratase; Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway.
 
     0.702
PP_2084
Putative regulator of ribonuclease activity; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
  
     0.679
PP_4464
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
    0.654
PP_1699
2-pyrone-4,6-dicarboxylic acid hydrolase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
   
 0.601
gllD
4-oxalomesaconate tautomerase; Catalyzes the tautomerization of the 4-oxalomesaconic acid keto (OMAketo) generated by GalA dioxygenase to 4-oxalomesaconic acid enol (OMAenol). Mediates the second step in gallate degradation pathway.
 
     0.581
PP_2055
Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
 
     0.545
glllA
Gallate dioxygenase; Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway.
 
   
 0.537
PP_4461
Major facilitator family transporter.
  
    0.533
PP_2293
DNA maturase B.
  
     0.418
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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