STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (335 aa)    
Predicted Functional Partners:
astD
N-succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
 
 
 0.999
astB
N-succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
  
 0.996
astA-I
Arginine N-succinyltransferase, subunit beta; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Amino acids and amines.
 
  
 0.977
astA-II
Arginine N-succinyltransferase, subunit alpha; Function experimentally demonstrated in the studied genus; enzyme; Energymetabolism : Amino acids and amines.
 
  
 0.956
gdhB
NAD-specific glutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines.
 
 
  0.915
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
  0.900
putA
Proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.900
PP_4476
Homologs of previously reported genes of unknown function.
  
    0.871
gdhA
Glutamate dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.807
PP_4399
Putative Glutamine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamine synthetase family.
   
 
  0.803
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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