Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tolCAgglutination protein. (452 aa)    
Predicted Functional Partners:
PP_0166
HlyD family secretion protein.
 
 0.987
paxB
Toxin secretion ATP-binding protein.
 
 
 0.986
PP_0168
Putative surface adhesion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
 
 0.953
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.912
emrA
Multidrug efflux transport system - membrane fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
  
 
 0.909
PP_0803
Protein secretion ABC efflux system, membrane fusion protein.
 
 
 0.865
mexB
Multidrug resistance protein MexB.
  
 
 0.852
PP_1798
Outer membrane efflux protein.
     
 0.842
PP_0804
Protein secretion ABC efflux system, permease and ATP-binding protein.
 
  
 0.836
PP_0164
Homologs of previously reported genes of unknown function; Unknown function.
 
   
 0.824
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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