STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4540Hydrolase, alpha/beta fold family. (270 aa)    
Predicted Functional Partners:
pcaC
4-carboxymuconolactone decarboxylase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
  
 0.916
PP_3648
Carboxymuconolactone decarboxylase family protein.
 
  
 0.906
PP_4551
Hydrolase, alpha/beta fold family.
  
   
 0.868
PP_4164
Alpha/beta hydrolase.
  
  
 0.864
PP_0256
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Central intermediary metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  
 0.839
PP_4690
Rieske 2Fe-2S family protein.
      
 0.839
ppiA
Peptidyl-prolyl cis-trans isomerase A (rotamase A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.818
mdaB
Modulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport.
      
 0.787
nuoG
NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
   
  
 0.756
PP_4539
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
    0.748
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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