Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
Score
PP_4566Putative drug/metabolite transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins. (291 aa)    
Predicted Functional Partners:
PP_2870
Putative spermidine/putrescine-binding periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Biologicalprocesses : Circulate.
  
   
 0.886
PP_4567
Homologs of previously reported genes of unknown function.
       0.773
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
 
    0.770
hemBB
Porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family.
      
 0.704
xre
Conserved protein of unknown function; Probable antitoxin component of a type II toxin-antitoxin (TA) system. In vivo probably neutralizes the toxic effect of cognate toxin Res.
  
   
 0.600
rhtA
Threonine and homoserine exporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Amino acids, peptides and amines.
      
 0.530
pduO
ATP:cob(I)alamin adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers; Belongs to the Cob(I)alamin adenosyltransferase family.
      
 0.425
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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