STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4588Putative oxidoreductase (nitroreductase family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (197 aa)    
Predicted Functional Partners:
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.565
ycaO
Cofactor of beta-methylthiolation of ribosomal protein S12; Function of homologous gene experimentally demonstrated in an other organism; factor; Unknown function.
  
  
 0.554
PP_4587
Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0260 family.
       0.546
PP_4586
Homologs of previously reported genes of unknown function.
       0.524
rbbA
Ribosome-associated ATPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinsynthesis : Ribosomal proteins.
  
  
 0.455
PP_4705
Glyoxalase.
 
    0.434
PP_4240
Putative Microcin b17 processing protein mcbd; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
   
   0.428
gltB
L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
     
 0.419
metH
Cobalamin-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.415
PP_5666
Putative microcin B17-like processing protein, McbB family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
    
   0.407
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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