Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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PP_4588Putative oxidoreductase (nitroreductase family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (197 aa)    
Predicted Functional Partners:
PP_4586
Homologs of previously reported genes of unknown function.
       0.598
PP_4587
Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0260 family.
       0.554
ycaO
Cofactor of beta-methylthiolation of ribosomal protein S12; Function of homologous gene experimentally demonstrated in an other organism; factor; Unknown function.
  
  
 0.540
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.498
rbbA
Ribosome-associated ATPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinsynthesis : Ribosomal proteins.
  
  
 0.482
tadA
tRNA-specific adenosine deaminase monomer; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.452
PP_4705
Glyoxalase.
 
    0.432
PP_4240
Putative Microcin b17 processing protein mcbd; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
   
   0.416
yadH
Putative ABC transporter - permease subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
  
  
 0.414
PP_2667
ABC transporter.
  
  
 0.414
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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