| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1709 | PP_3205 | PP_1709 | PP_3205 | Fumarylacetoacetate hydrolase family protein. | Fumarylacetoacetate hydrolase family protein. | 0.900 |
| PP_1709 | hmgA | PP_1709 | PP_4621 | Fumarylacetoacetate hydrolase family protein. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | 0.866 |
| PP_1709 | hmgB | PP_1709 | PP_4620 | Fumarylacetoacetate hydrolase family protein. | Fumarylacetoacetase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.941 |
| PP_1709 | hmgC | PP_1709 | PP_4619 | Fumarylacetoacetate hydrolase family protein. | Maleylacetoacetate isomerase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.735 |
| PP_1709 | hpd | PP_1709 | PP_3433 | Fumarylacetoacetate hydrolase family protein. | 4-hydroxyphenylpyruvate dioxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. | 0.502 |
| PP_3205 | PP_1709 | PP_3205 | PP_1709 | Fumarylacetoacetate hydrolase family protein. | Fumarylacetoacetate hydrolase family protein. | 0.900 |
| PP_3205 | hmgA | PP_3205 | PP_4621 | Fumarylacetoacetate hydrolase family protein. | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | 0.960 |
| PP_3205 | hmgB | PP_3205 | PP_4620 | Fumarylacetoacetate hydrolase family protein. | Fumarylacetoacetase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.949 |
| PP_3205 | hmgC | PP_3205 | PP_4619 | Fumarylacetoacetate hydrolase family protein. | Maleylacetoacetate isomerase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.997 |
| PP_3205 | hpd | PP_3205 | PP_3433 | Fumarylacetoacetate hydrolase family protein. | 4-hydroxyphenylpyruvate dioxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. | 0.918 |
| PP_3205 | phhA | PP_3205 | PP_4490 | Fumarylacetoacetate hydrolase family protein. | Phenylalanine-4-hydroxylase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.697 |
| hmgA | PP_1709 | PP_4621 | PP_1709 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Fumarylacetoacetate hydrolase family protein. | 0.866 |
| hmgA | PP_3205 | PP_4621 | PP_3205 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Fumarylacetoacetate hydrolase family protein. | 0.960 |
| hmgA | hmgB | PP_4621 | PP_4620 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Fumarylacetoacetase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.999 |
| hmgA | hmgC | PP_4621 | PP_4619 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Maleylacetoacetate isomerase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.999 |
| hmgA | hmgR | PP_4621 | PP_4622 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Hmg transcriptional repressor; Function experimentally demonstrated in the studied species; regulator; Energy metabolism. | 0.868 |
| hmgA | hpd | PP_4621 | PP_3433 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | 4-hydroxyphenylpyruvate dioxygenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines. | 0.999 |
| hmgA | phhA | PP_4621 | PP_4490 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Phenylalanine-4-hydroxylase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.976 |
| hmgA | phhB | PP_4621 | PP_4491 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA (By similarity); Belongs to the pterin-4-alpha-carbinolamine dehydratase family. | 0.765 |
| hmgA | tyrB | PP_4621 | PP_1972 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the ar omatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate. | Aromatic-amino-acid aminotransferase; Function experimentally demonstrated in the studied strain; enzyme; Aminoacidbiosynthesis : Aspartate family. | 0.831 |