Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_4640Homologs of previously reported genes of unknown function; Unknown function. (65 aa)    
Predicted Functional Partners:
yjiY
Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Cellularprocesses : Adaptations to atypical conditions.
 
  
 0.992
zinU
P-loop guanosine triphosphatase-dependent zinc chaperone; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Heme, porphyrin, and cobalamin.
  
 0.934
PP_4642
Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
  
    0.508
PP_3323
CobW/P47K family protein.
  
  
 0.463
cobW
Protein CobW.
  
  
 0.463
PP_5359
CobW/P47K family protein.
  
  
 0.463
PP_5361
47 kDa protein.
  
  
 0.463
PP_1890
Type 1 pili chaperone protein FimC.
  
     0.451
fimD
Type 1 pili subunit FimD.
  
     0.447
PP_2968
Putative nickel/cobalt transporter, high-affinity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins; Belongs to the NiCoT transporter (TC 2.A.52) family.
  
     0.432
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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