| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1841 | PP_4642 | PP_1841 | PP_4642 | Cytochrome c family protein. | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | 0.768 |
| PP_4333 | PP_4642 | PP_4333 | PP_4642 | CheW domain protein. | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | 0.745 |
| PP_4333 | PP_5209 | PP_4333 | PP_5209 | CheW domain protein. | Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | 0.856 |
| PP_4333 | cheR | PP_4333 | PP_4392 | CheW domain protein. | Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor. | 0.681 |
| PP_4333 | fleQ | PP_4333 | PP_4373 | CheW domain protein. | Transcriptional regulator FleQ. | 0.480 |
| PP_4333 | flgM | PP_4333 | PP_4395 | CheW domain protein. | Negative regulator of flagellin synthesis FlgM. | 0.854 |
| PP_4333 | fliM | PP_4333 | PP_4358 | CheW domain protein. | Flagellar synthesis, switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.807 |
| PP_4333 | ycgR | PP_4333 | PP_4397 | CheW domain protein. | Flagellar brake protein YcgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity). Binds c-di-GMP with a dissociation constant of 165 nM. Binds 2 intercalated (c-di-GMP) dimers per subunit. | 0.695 |
| PP_4642 | PP_1841 | PP_4642 | PP_1841 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Cytochrome c family protein. | 0.768 |
| PP_4642 | PP_4333 | PP_4642 | PP_4333 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | CheW domain protein. | 0.745 |
| PP_4642 | PP_5209 | PP_4642 | PP_5209 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | 0.705 |
| PP_4642 | bcsA | PP_4642 | PP_2635 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Cellulose synthase and translocator subunit; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose. | 0.811 |
| PP_4642 | bcsG | PP_4642 | PP_2632 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Putative endoglucanase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides. | 0.825 |
| PP_4642 | cheR | PP_4642 | PP_4392 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. Methylates the McpS chemotaxis receptor. | 0.868 |
| PP_4642 | fleQ | PP_4642 | PP_4373 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Transcriptional regulator FleQ. | 0.795 |
| PP_4642 | flgM | PP_4642 | PP_4395 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Negative regulator of flagellin synthesis FlgM. | 0.841 |
| PP_4642 | fliM | PP_4642 | PP_4358 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Flagellar synthesis, switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. | 0.811 |
| PP_4642 | ycgR | PP_4642 | PP_4397 | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | Flagellar brake protein YcgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity). Binds c-di-GMP with a dissociation constant of 165 nM. Binds 2 intercalated (c-di-GMP) dimers per subunit. | 0.865 |
| PP_5209 | PP_4333 | PP_5209 | PP_4333 | Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | CheW domain protein. | 0.856 |
| PP_5209 | PP_4642 | PP_5209 | PP_4642 | Conserved exported protein of unknown function; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. | 0.705 |
