STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fpr-IIferredoxin--NADP(+) reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. (258 aa)    
Predicted Functional Partners:
fdxA
Ferredoxin 1; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
     
 0.872
iscR
DNA-binding transcriptional dual regulator 2Fe-2S cluster IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
  
  
 0.746
rlmG
Ribosomal RNA large subunit methyltransferase G; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
  
    0.667
soxR
MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
      
 0.655
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.648
rsmC
Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.
      
 0.634
oxyR
Oxidative and nitrosative stress transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription; Belongs to the LysR transcriptional regulatory family.
      
 0.540
PP_4647
Transcriptional regulator, LuxR family; Function of strongly homologous gene; regulator; Transcription.
  
    0.486
grxD
Monothiol glutaredoxin 4; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport; Belongs to the glutaredoxin family. Monothiol subfamily.
   
  
 0.427
iscX
Donor of Fe2+ and regulator of cysteine desulfurase activity; Function of homologous gene experimentally demonstrated in an other organism; regulator; Proteinfate : Protein folding and stabilization.
      
 0.422
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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