Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_4647Transcriptional regulator, LuxR family; Function of strongly homologous gene; regulator; Transcription. (235 aa)    
Predicted Functional Partners:
rlmG
Ribosomal RNA large subunit methyltransferase G; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
     
 0.903
PP_0170
ABC transporter, periplasmic binding protein.
      
 0.881
PP_4136
Transcriptional regulator, LuxR family.
 
 
 
 0.758
rpoS
RNA polymerase, sigma S (sigma 38) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
  
 0.659
tauA
Taurine ABC transporter periplasmic binding subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Centralintermediarymetabolism : Sulfur metabolism.
      
 0.631
uvrY
Two-componenent system BarA/UvrY - regulatory subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
  
 
 0.622
rhlB
ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
      
 0.584
crp
DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Transcription.
   
  
 0.581
phaG
(R)-3-hydroxydecanoyl-ACP:CoA transacylase; Catalyzes the transfer of the acyl moiety from in vitro synthesized 3-hydroxydecanoyl-CoA to acyl carrier protein.
   
  
 0.525
PP_0772
Metallo-beta-lactamase family protein.
    
 
 0.520
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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