STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cioBUbiquinol oxidase subunit II, cyanide insensitive. (335 aa)    
Predicted Functional Partners:
cioA
Ubiquinol oxidase subunit I, cyanide insensitive.
 0.999
PP_4649
Homologs of previously reported genes of unknown function.
  
    0.944
PP_1832
Putative Oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.860
opdB
Proline-specific outer membrane porin D; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Porins.
      
 0.766
pntAA
Pyridine nucleotide transhydrogenase subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Pyridine nucleotides.
   
  
 0.693
cyoD
Cytochrome bo terminal oxidase subunit IV; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic.
     
 0.614
nuoA
NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
      
 0.597
nuoN
NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
      
 0.593
pntB
Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
   
  
 0.564
PP_3338
Putative cytochrome bd-type quinol oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energy metabolism.
  
  
 
0.547
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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