| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_4652 | purP | PP_4652 | PP_4653 | Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | adenine:H+ symporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Circulate. | 0.441 |
| PP_4652 | trmA | PP_4652 | PP_4654 | Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | tRNA/tmRNA (uracil-C(5))-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.443 |
| apt | guaA | PP_4266 | PP_1032 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.987 |
| apt | purC | PP_4266 | PP_1240 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.432 |
| apt | purD | PP_4266 | PP_4823 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylamine--glycine ligase. | 0.416 |
| apt | purH | PP_4266 | PP_4822 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Purine ribonucleotide biosynthesis. | 0.952 |
| apt | purL | PP_4266 | PP_1037 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.765 |
| apt | purP | PP_4266 | PP_4653 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | adenine:H+ symporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Circulate. | 0.434 |
| apt | uraA | PP_4266 | PP_0745 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative uracil permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.435 |
| guaA | apt | PP_1032 | PP_4266 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.987 |
| guaA | purC | PP_1032 | PP_1240 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.686 |
| guaA | purD | PP_1032 | PP_4823 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine--glycine ligase. | 0.916 |
| guaA | purH | PP_1032 | PP_4822 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Purine ribonucleotide biosynthesis. | 0.920 |
| guaA | purL | PP_1032 | PP_1037 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.973 |
| guaA | purP | PP_1032 | PP_4653 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | adenine:H+ symporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Circulate. | 0.487 |
| guaA | trmA | PP_1032 | PP_4654 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA/tmRNA (uracil-C(5))-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.426 |
| guaA | uraA | PP_1032 | PP_0745 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative uracil permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.519 |
| purC | apt | PP_1240 | PP_4266 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.432 |
| purC | guaA | PP_1240 | PP_1032 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.686 |
| purC | purD | PP_1240 | PP_4823 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase. | 0.981 |