Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdaBModulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport. (223 aa)    
Predicted Functional Partners:
nfnB
6,7-dihydropteridine reductase; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
  
 0.928
PP_3720
Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
   
 0.900
PP_4690
Rieske 2Fe-2S family protein.
  
  
 0.819
PP_4540
Hydrolase, alpha/beta fold family.
      
 0.815
PP_4551
Hydrolase, alpha/beta fold family.
      
 0.815
ecd
Flavoprotein; Belongs to the flavin oxidoreductase frp family.
  
  
 0.804
chrR
Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...]
     
 0.765
azoR2
FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.
     
 0.718
kefB-II
Glutathione-regulated potassium/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.662
kefB-III
Glutathione-regulated potassium/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.662
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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