STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
mmsB3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)    
Predicted Functional Partners:
mmsA-II
Methylmalonate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
 
 0.996
PP_3491
Enoly-coenzyme A hydratase/isomerase family protein.
  
 0.982
mmsA-I
Methylmalonate-semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme.
 
 
 0.962
PP_1412
3-hydroxyisobutyryl-CoA hydrolase; Function of strongly homologous gene; enzyme.
 
 0.955
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
 
 0.915
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
  
 0.913
PP_0596
Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
 
 0.892
acd
Short-chain acyl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Biologicalprocesses : Scavenge (Catabolism).
  
 
 0.858
acsA-II
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.840
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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