STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmsB3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)    
Predicted Functional Partners:
mmsA-II
Methylmalonate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
 
 0.997
PP_3491
Enoly-coenzyme A hydratase/isomerase family protein.
  
 0.967
mmsA-I
Methylmalonate-semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme.
 
 
 0.959
PP_1143
3-hydroxyisobutyrate dehydrogenase family protein.
  
  
 
0.920
fadB
enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.920
PP_1412
3-hydroxyisobutyryl-CoA hydrolase; Function of strongly homologous gene; enzyme.
 
 0.917
amaB
L-piperidine-6-carboxylate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family.
  
 
 0.910
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
    0.906
PP_0596
Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.900
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
 
 0.900
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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