Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mmsA-IIMethylmalonate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Scavenge (Catabolism). (508 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.996
PP_0596
Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.941
prpC
Methylcitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the citrate synthase family.
  
 0.939
acd
Short-chain acyl-CoA dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Biologicalprocesses : Scavenge (Catabolism).
   
 
 0.932
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
   
 0.926
fadA
3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.922
pcaF-II
Beta-ketoadipyl CoA thiolase, beta component; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.920
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
   
 
 0.917
PP_2213
Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.916
acsA-I
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.916
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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