STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrPMethionine sulfoxide reductase catalytic subunit; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able [...] (341 aa)    
Predicted Functional Partners:
msrQ
Methionine sulfoxide reductase heme-binding subunit; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase ca [...]
 
  
 0.993
PP_4677
CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
    0.895
PP_2401
Homologs of previously reported genes of unknown function.
  
  
 0.782
PP_0103
Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.599
ccoP-I
Cytochrome c oxidase subunit, cbb3-type; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
   
 
 0.570
ccoP-II
Cytochrome c oxidase subunit, cbb3-type; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
   
 
 0.570
moaE
Molybdopterin synthase large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Molybdopterin.
 
   
 0.564
PP_2641
Iron-sulfur cluster-binding protein.
  
  
 0.554
PP_0180
Putative cytochrome c family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 
 0.536
PP_1659
Homologs of previously reported genes of unknown function.
   
 
 0.528
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.