STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4682Conserved protein of unknown function containing tetratricopeptide repeat domain; Homologs of previously reported genes of unknown function; Unknown function. (266 aa)    
Predicted Functional Partners:
mrcB
Transglycosylase/transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
  
 0.955
PP_4681
Homologs of previously reported genes of unknown function.
       0.869
lptE
Putative Lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
  
 0.647
lptC
Conserved exported protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
  
     0.636
PP_4684
Conserved protein of unknown function with kinase-like domain; Homologs of previously reported genes of unknown function; Unknown function.
  
    0.622
PP_5201
Conserved protein of unknown function, UPF0149 family; Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0149 family.
  
    0.609
PP_2893
Homologs of previously reported genes of unknown function.
  
     0.602
PP_1236
Putative Glycine cleavage system transcriptional repressor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.600
PP_5358
Homologs of previously reported genes of unknown function.
  
     0.553
PP_1658
Homologs of previously reported genes of unknown function.
  
     0.542
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.