STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4684Conserved protein of unknown function with kinase-like domain; Homologs of previously reported genes of unknown function; Unknown function. (520 aa)    
Predicted Functional Partners:
PP_3230
Phosphoribosyl transferase domain protein.
 
  
 0.728
mgtA
Magnesium transporter, ATP-dependent; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energymetabolism : ATP-proton motive force interconversion.
 
    0.721
PP_4685
Homologs of previously reported genes of unknown function.
       0.716
mrcB
Transglycosylase/transpeptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
    0.645
PP_4682
Conserved protein of unknown function containing tetratricopeptide repeat domain; Homologs of previously reported genes of unknown function; Unknown function.
  
    0.622
PP_4681
Homologs of previously reported genes of unknown function.
       0.611
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
    0.604
PP_2052
Putative bifunctional enzyme: sugar-phosphatase/mannitol-1-phosphate 5-dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energy metabolism.
  
    0.588
PP_2162
Putative phosphonoacetaldehyde phosphonohydrolase-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
    0.585
phnX
Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
  
    0.585
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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