STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4696Nitrogen regulation protein NR(I). (480 aa)    
Predicted Functional Partners:
PP_4695
Sensory box histidine kinase.
 
 
 0.994
PP_5704
Homologs of previously reported genes of unknown function.
     
 0.983
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
  
 0.794
PP_3558
Putative Amino acid transporter, periplasmic amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  
 0.738
PP_3559
Glycine betaine ABC transporter (permease); Function of strongly homologous gene; transporter; Transportandbindingproteins : Amino acids, peptides and amines.
   
  
 0.738
PP_2810
Homologs of previously reported genes of unknown function.
     
 0.734
PP_4959
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
  
 
0.631
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 
 0.614
PP_4988
Signal transduction histidine kinase CheA/CheY-like receiver; Function of strongly homologous gene; enzyme; Signaltransduction : Two-component systems.
 
 
 0.588
urtA
Putative Urea ABC transporter, periplasmic protein; Function of homologous gene experimentally demonstrated in an other organism; putative transporter; Transport and binding proteins.
 
 
    0.531
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (60%) [HD]