Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lldPL-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (556 aa)    
Predicted Functional Partners:
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
  
 0.996
dld2
D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
  
 0.987
pdhR
DNA-binding transcriptional dual regulator, LldR-L-lactate; Function experimentally demonstrated in the studied genus; regulator; Energymetabolism : Aerobic.
  
 0.935
ydiJ
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
 
  
 0.754
glcF
Glycolate oxidase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
  
 0.661
glcC
Transcriptional dual regulator GlcC-Glycolate; Function of homologous gene experimentally demonstrated in an other organism; regulator; Energy metabolism.
 
  
 0.645
fruA
Fructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism.
  
   
 0.633
pta
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.612
putA
Proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
      
 0.602
mdh
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
  
 0.541
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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