node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_1389 | aceE | PP_1389 | PP_0339 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.900 |
PP_1389 | ldhA | PP_1389 | PP_1649 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | D-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.911 |
PP_1389 | lldD | PP_1389 | PP_4736 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. | 0.931 |
PP_1389 | maeB | PP_1389 | PP_5085 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.913 |
PP_1389 | ppsA | PP_1389 | PP_2082 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.908 |
PP_1389 | pycB | PP_1389 | PP_5346 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.900 |
PP_1389 | pyk | PP_1389 | PP_4301 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.911 |
PP_1389 | pykA | PP_1389 | PP_1362 | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family. | 0.911 |
aceE | PP_1389 | PP_0339 | PP_1389 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. | 0.900 |
aceE | ldhA | PP_0339 | PP_1649 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | D-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.917 |
aceE | lldD | PP_0339 | PP_4736 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. | 0.918 |
aceE | maeB | PP_0339 | PP_5085 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.940 |
aceE | ppsA | PP_0339 | PP_2082 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.914 |
aceE | pycB | PP_0339 | PP_5346 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.954 |
aceE | pyk | PP_0339 | PP_4301 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.925 |
aceE | pykA | PP_0339 | PP_1362 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family. | 0.937 |
dld2 | lldD | PP_4737 | PP_4736 | D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. | 0.986 |
dld2 | lldP | PP_4737 | PP_4735 | D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.982 |
dld2 | maeB | PP_4737 | PP_5085 | D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.478 |
dld2 | pycB | PP_4737 | PP_5346 | D-lactate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.518 |