Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hsdRType I restriction enzyme EcoAI R protein. (787 aa)    
Predicted Functional Partners:
hsdM
Type I restriction enzyme EcoEI M protein.
 
 
 0.999
hsdS
Type I restriction-modification system, S subunit.
 
 
 0.996
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
      
 0.874
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
      
 0.870
rbsR
DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions.
      
 0.816
PP_4743
Homologs of previously reported genes of unknown function.
 
     0.811
PP_5711
Protein of unknown function; No homology to any previously reported sequences; Unknown function.
       0.514
PP_0941
Putative ribosome associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Transport and binding proteins; Belongs to the UPF0307 family.
      
 0.496
PP_3067
Homologs of previously reported genes of unknown function; Unknown function.
  
  
 0.477
PP_3691
DNA helicase-related protein.
  
    0.477
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (66%) [HD]