Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hsdMType I restriction enzyme EcoEI M protein. (489 aa)    
Predicted Functional Partners:
hsdR
Type I restriction enzyme EcoAI R protein.
 
 
 0.999
hsdS
Type I restriction-modification system, S subunit.
 
 0.999
PP_4743
Homologs of previously reported genes of unknown function.
 
  
 0.913
PP_5711
Protein of unknown function; No homology to any previously reported sequences; Unknown function.
     
 0.760
PP_0941
Putative ribosome associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Transport and binding proteins; Belongs to the UPF0307 family.
      
 0.616
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
      
 0.615
PP_3691
DNA helicase-related protein.
  
  
 0.589
PP_3680
Homologs of previously reported genes of unknown function.
  
  
 0.581
yedA
Amino acid exporter for phenylalanine, threonine; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Circulate.
      
 0.548
uvrB
Excinuclease UvrABC protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissocia [...]
    
 
 0.524
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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