Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hrpBATP-dependent helicase HrpB. (842 aa)    
Predicted Functional Partners:
fieF
Divalent cation efflux transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
   0.751
cysB
Transcriptional dual regulator / CysB-O-acetyl-L-serine; Function of homologous gene experimentally demonstrated in an other organism; regulator; Aminoacidbiosynthesis : Serine family; Belongs to the LysR transcriptional regulatory family.
     
 0.743
rnd
Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.
  
 0.725
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
 0.721
fliQ
Flagellar export apparatus subunit; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
      
 0.716
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
  0.709
fliP
Flagellar export apparatus subunit; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
      
 0.707
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.699
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
 0.657
cysI
Sulphite reductase hemoprotein, beta subunit.
      
 0.656
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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