| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_4799 | PP_4802 | PP_4799 | PP_4802 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | 0.598 |
| PP_4799 | amiC | PP_4799 | PP_4897 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.623 |
| PP_4799 | amiD | PP_4799 | PP_0130 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.617 |
| PP_4799 | dacA | PP_4799 | PP_4803 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | 0.738 |
| PP_4799 | lipA | PP_4799 | PP_4800 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.597 |
| PP_4799 | lipB | PP_4799 | PP_4801 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.605 |
| PP_4799 | mpl | PP_4799 | PP_0547 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.594 |
| PP_4799 | msbA | PP_4799 | PP_4935 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.654 |
| PP_4799 | nagZ | PP_4799 | PP_2145 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | beta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.559 |
| PP_4799 | wzy | PP_4799 | PP_4936 | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | O-antigen polymerase. | 0.740 |
| PP_4802 | PP_4799 | PP_4802 | PP_4799 | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.598 |
| PP_4802 | dacA | PP_4802 | PP_4803 | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | 0.832 |
| PP_4802 | lipA | PP_4802 | PP_4800 | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.903 |
| PP_4802 | lipB | PP_4802 | PP_4801 | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.930 |
| amiC | PP_4799 | PP_4897 | PP_4799 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.623 |
| amiC | nagZ | PP_4897 | PP_2145 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | beta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.659 |
| amiD | PP_4799 | PP_0130 | PP_4799 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.617 |
| amiD | nagZ | PP_0130 | PP_2145 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | beta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.692 |
| dacA | PP_4799 | PP_4803 | PP_4799 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Putative Muramoyltetrapeptide carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.738 |
| dacA | PP_4802 | PP_4803 | PP_4802 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Putative lipoate regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the UPF0250 family. | 0.832 |
