| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiC | ftsA | PP_4897 | PP_1341 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.653 |
| amiC | mltB | PP_4897 | PP_4805 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.480 |
| amiC | mrdA-II | PP_4897 | PP_4807 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Transpeptidase (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.560 |
| amiC | mrdB | PP_4897 | PP_4806 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Murein transpeptidase factor; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.626 |
| amiC | rlpA | PP_4897 | PP_4804 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.781 |
| ftsA | amiC | PP_1341 | PP_4897 | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.653 |
| ftsA | lpxC | PP_1341 | PP_1343 | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.923 |
| ftsA | mrdA-II | PP_1341 | PP_4807 | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Transpeptidase (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.613 |
| ftsA | mrdB | PP_1341 | PP_4806 | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Murein transpeptidase factor; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.681 |
| ftsA | rlpA | PP_1341 | PP_4804 | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.917 |
| lpxC | ftsA | PP_1343 | PP_1341 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Essential cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.923 |
| lpxC | phoQ | PP_1343 | PP_1187 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Sensor protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. | 0.509 |
| lpxC | rlpA | PP_1343 | PP_4804 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.800 |
| mltB | amiC | PP_4805 | PP_4897 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.480 |
| mltB | mrdA-II | PP_4805 | PP_4807 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Transpeptidase (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.814 |
| mltB | mrdB | PP_4805 | PP_4806 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Murein transpeptidase factor; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.833 |
| mltB | proA | PP_4805 | PP_4811 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.651 |
| mltB | rlmH | PP_4805 | PP_4808 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 23S rRNA m3psi1915 methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.745 |
| mltB | rlpA | PP_4805 | PP_4804 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.909 |
| mltB | rsfS | PP_4805 | PP_4809 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.743 |