| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_5202 | mltB | PP_5202 | PP_4805 | Putative cell division protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.496 |
| dacA | mltB | PP_4803 | PP_4805 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 0.638 |
| dacA | mrdA-II | PP_4803 | PP_4807 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Transpeptidase (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.945 |
| dacA | mrdB | PP_4803 | PP_4806 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Murein transpeptidase factor; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.725 |
| dacA | nadD | PP_4803 | PP_4810 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.447 |
| dacA | proA | PP_4803 | PP_4811 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.466 |
| dacA | rlmH | PP_4803 | PP_4808 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | 23S rRNA m3psi1915 methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.674 |
| dacA | rlpA | PP_4803 | PP_4804 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.653 |
| dacA | rsfS | PP_4803 | PP_4809 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.509 |
| dacA | secB | PP_4803 | PP_5053 | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.543 |
| mltB | PP_5202 | PP_4805 | PP_5202 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Putative cell division protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.496 |
| mltB | dacA | PP_4805 | PP_4803 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family. | 0.638 |
| mltB | mrdA-II | PP_4805 | PP_4807 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Transpeptidase (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.814 |
| mltB | mrdB | PP_4805 | PP_4806 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Murein transpeptidase factor; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.833 |
| mltB | nadD | PP_4805 | PP_4810 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.642 |
| mltB | proA | PP_4805 | PP_4811 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.651 |
| mltB | rlmH | PP_4805 | PP_4808 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | 23S rRNA m3psi1915 methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.745 |
| mltB | rlpA | PP_4805 | PP_4804 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.909 |
| mltB | rsfS | PP_4805 | PP_4809 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.743 |
| mltB | secB | PP_4805 | PP_5053 | Membrane-bound lytic murein transglycosylase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.557 |