| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_4821 | dusB | PP_4821 | PP_4820 | Putative Fis-like DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.989 |
| PP_4821 | prmA | PP_4821 | PP_4818 | Putative Fis-like DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.875 |
| PP_4821 | rnpA | PP_4821 | PP_0008 | Putative Fis-like DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.509 |
| dusB | PP_4821 | PP_4820 | PP_4821 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Putative Fis-like DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.989 |
| dusB | hinT | PP_4820 | PP_0428 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | 0.650 |
| dusB | prmA | PP_4820 | PP_4818 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.840 |
| dusB | rlmB | PP_4820 | PP_4879 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.878 |
| dusB | rnpA | PP_4820 | PP_0008 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.666 |
| dusB | rsmH | PP_4820 | PP_1329 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.768 |
| dusB | rsmI | PP_4820 | PP_1326 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 16S rRNA 2'-O-ribose C1402 methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.767 |
| dusB | trmK | PP_4820 | PP_3495 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Construct biomass (Anabolism). | 0.869 |
| dusB | truA | PP_4820 | PP_1994 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | tRNA pseudouridine (38-40)synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.840 |
| dusB | tsaE | PP_4820 | PP_4898 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | ATPase; Function of strongly homologous gene; enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.890 |
| hinT | dusB | PP_0428 | PP_4820 | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.650 |
| hinT | rlmB | PP_0428 | PP_4879 | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.720 |
| hinT | rsmH | PP_0428 | PP_1329 | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.525 |
| hinT | trmK | PP_0428 | PP_3495 | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | tRNA (adenine(22)-N(1))-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Construct biomass (Anabolism). | 0.645 |
| hinT | tsaE | PP_0428 | PP_4898 | Aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain. | ATPase; Function of strongly homologous gene; enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.662 |
| prmA | PP_4821 | PP_4818 | PP_4821 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | Putative Fis-like DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.875 |
| prmA | dusB | PP_4818 | PP_4820 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.840 |