STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobIPrecorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (244 aa)    
Predicted Functional Partners:
cobJ
Precorrin-3B C17-methyltransferase.
  
 0.999
cobH
Precorrin-8X methylmutase.
  
 0.991
cobG
Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers.
 
 
 0.991
cobL
precorrin-6Y C(5,15)-methyltransferase; Function of strongly homologous gene; enzyme.
  
 0.986
cobK
Precorrin-6x reductase.
 
  
 0.974
cysG
Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
 0.957
cobA
Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.937
cbiD
Putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.918
PP_0188
Putative Uroporphyrin-III C-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
  0.900
cobM
Precorrin-4 C(11)-methyltransferase.
 
  
0.879
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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