| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1703 | cobA | PP_1703 | PP_2090 | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.640 |
| PP_1703 | cobG | PP_1703 | PP_4829 | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | 0.904 |
| PP_1703 | cysG | PP_1703 | PP_3999 | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.841 |
| PP_1703 | cysNC | PP_1703 | PP_1304 | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.991 |
| cobA | PP_1703 | PP_2090 | PP_1703 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.640 |
| cobA | cobG | PP_2090 | PP_4829 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | 0.920 |
| cobA | cobH | PP_2090 | PP_4828 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-8X methylmutase. | 0.794 |
| cobA | cobI | PP_2090 | PP_4827 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.936 |
| cobA | cobJ | PP_2090 | PP_4826 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-3B C17-methyltransferase. | 0.907 |
| cobA | cobK | PP_2090 | PP_4832 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-6x reductase. | 0.725 |
| cobA | cobL | PP_2090 | PP_4830 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | precorrin-6Y C(5,15)-methyltransferase; Function of strongly homologous gene; enzyme. | 0.872 |
| cobA | cobM | PP_2090 | PP_3410 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-4 C(11)-methyltransferase. | 0.607 |
| cobA | cysG | PP_2090 | PP_3999 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.961 |
| cobA | cysNC | PP_2090 | PP_1304 | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.776 |
| cobG | PP_1703 | PP_4829 | PP_1703 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.904 |
| cobG | cobA | PP_4829 | PP_2090 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.920 |
| cobG | cobH | PP_4829 | PP_4828 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Precorrin-8X methylmutase. | 0.998 |
| cobG | cobI | PP_4829 | PP_4827 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.994 |
| cobG | cobJ | PP_4829 | PP_4826 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Precorrin-3B C17-methyltransferase. | 0.998 |
| cobG | cobK | PP_4829 | PP_4832 | Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers. | Precorrin-6x reductase. | 0.972 |