Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobLprecorrin-6Y C(5,15)-methyltransferase; Function of strongly homologous gene; enzyme. (403 aa)    
Predicted Functional Partners:
cobM
Precorrin-4 C(11)-methyltransferase.
  
 0.999
cobJ
Precorrin-3B C17-methyltransferase.
 
  
 0.999
cobH
Precorrin-8X methylmutase.
 
 
 0.999
cbiD
Putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 0.999
cobK
Precorrin-6x reductase.
 
 
 0.999
cobN
Aerobic cobaltochelatase subunit CobN.
 
  
 0.992
cobI
Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
  
 0.986
cobQ
Adenosyl-cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.977
cobG
Putative precorrin-3B synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biosynthesis of cofactors, prosthetic groups, and carriers.
 
  
 0.969
cobD
Subunit of adenosylcobinamide-phosphate synthase beta component; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.965
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.