| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_4677 | alr | PP_4677 | PP_3722 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | 0.900 |
| PP_4677 | glyA-I | PP_4677 | PP_0322 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| PP_4677 | glyA-II | PP_4677 | PP_0671 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| PP_4677 | pssA | PP_4677 | PP_3664 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis. | 0.906 |
| PP_4677 | serB | PP_4677 | PP_4909 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase; Function experimentally demonstrated in the studied genus; enzyme; Aminoacidbiosynthesis : Serine family. | 0.907 |
| PP_4677 | tdcG-I | PP_4677 | PP_0297 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| PP_4677 | tdcG-II | PP_4677 | PP_0987 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| PP_4677 | tdcG-III | PP_4677 | PP_3144 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| PP_4677 | trpB | PP_4677 | PP_0083 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| alr | PP_4677 | PP_3722 | PP_4677 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| alr | glyA-I | PP_3722 | PP_0322 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| alr | glyA-II | PP_3722 | PP_0671 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| alr | pssA | PP_3722 | PP_3664 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | CDP-diacylglycerol--serine O-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis. | 0.915 |
| alr | serB | PP_3722 | PP_4909 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | Phosphoserine phosphatase; Function experimentally demonstrated in the studied genus; enzyme; Aminoacidbiosynthesis : Serine family. | 0.920 |
| alr | tdcG-I | PP_3722 | PP_0297 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.903 |
| alr | tdcG-II | PP_3722 | PP_0987 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.903 |
| alr | tdcG-III | PP_3722 | PP_3144 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | L-serine dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.905 |
| alr | trpB | PP_3722 | PP_0083 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| glyA-I | PP_4677 | PP_0322 | PP_4677 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA-I | alr | PP_0322 | PP_3722 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes 9 of the 19 natural chiral amino acids known, including both positively charged amino acids (Lys, Arg and His) and non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Gln and Asn). Among these amino acids, activity is the highest with lysine and arginine, and poor or very poor with the others. Plays a primary role in the catabolism of basic amino acid, that allows P.putida strain KT2440 to grow on L-Lys and L-Arg as the sole source of carbon and nitrogen, through conversion [...] | 0.920 |
