Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cyaBCyclolysin secretion/processing ATP-binding protein CyaB. (731 aa)    
Predicted Functional Partners:
PP_4926
HlyD family secretion protein.
 
 0.979
PP_2307
Homologs of previously reported genes of unknown function.
      
 0.970
PP_4924
Serine protease, subtilase family.
 
  
 0.884
PP_0166
HlyD family secretion protein.
 
 0.836
PP_1797
HlyD family secretion protein.
 
 0.836
PP_3849
Putative calcium-binding protein, hemolysin-type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier; Cellular processes.
 
  
 0.834
PP_0803
Protein secretion ABC efflux system, membrane fusion protein.
 
 0.830
hasE
Metalloprotease secretion protein.
 
 
 0.802
cyaA
Adenylate cyclase; Function experimentally demonstrated in the studied strain; enzyme.
   
  
 0.753
pde
3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
      
 0.548
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.