STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldEHeptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (473 aa)    
Predicted Functional Partners:
diaA
Factor modulating bacterial replication archosome assembly; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.999
gmhB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. Belongs to the gmhB family.
  
 0.989
waaF
ADP-heptose:LPS heptosyltransferase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
  
 0.870
waaC
ADP-heptose:LPS heptosyltransferase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.869
degS
Quality control serine endoprotease DegS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
     
 0.834
tolR
Subunit of a proton-driven complex used for maintenance of outer membrane stability; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
      
 0.747
prtN
Transcription regulatory protein PrtN.
      
 0.738
wzy
O-antigen polymerase.
     
 0.655
mreB
Cell wall structural actin-like protein MreB; Function of homologous gene experimentally demonstrated in an other organism; structure; Cellularprocesses : Cell division.
     
 0.625
msbA
Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
 
   
 0.602
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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