STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaPNhaP-type Na+/H+ and K+/H+ antiporters; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Cations and iron carrying compounds. (411 aa)    
Predicted Functional Partners:
nhaB
Na(+)/H(+) antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
      
 0.843
mrp
ATP-dependent Fe-S cluster transferase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
      
 0.762
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
   
  
 0.762
kup
Probable potassium transport system protein kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
      
 0.646
PP_4973
Homologs of previously reported genes of unknown function; Unknown function.
  
  
 0.504
PP_4972
Homologs of previously reported genes of unknown function.
       0.473
cvrA
K(+)/H(+) antiporter NhaP2; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
  
  
0.464
msuE
FMN reductase (NADPH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Sulfur metabolism.
      
 0.440
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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