Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
nhaPNhaP-type Na+/H+ and K+/H+ antiporters; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Cations and iron carrying compounds. (411 aa)    
Predicted Functional Partners:
nhaB
Na(+)/H(+) antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
      
 0.837
mrp
ATP-dependent Fe-S cluster transferase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
      
 0.770
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
      
 0.755
PP_4972
Homologs of previously reported genes of unknown function.
       0.621
PP_4973
Homologs of previously reported genes of unknown function; Unknown function.
       0.569
cvrA
K(+)/H(+) antiporter NhaP2; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
  
  
0.515
osmC
Stress-induced peroxiredoxin, lipoyl-dependent peroxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellularprocesses : Adaptations to atypical conditions.
  
  
 0.425
ohr
Organic hydroperoxide resistance protein.
   
  
 0.417
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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